Pan genome

Introduction


The pan-genome encompasses all genes within a population, consisting of core genes (presentin all samples), dispensable genes (found in some samples), and unique genes (exclusive tospecific samples). Core genes indicate species stability and are typically linked to species’ biological functions and key traits; dispensable and unique genes reflect species-specific biological attributes and adaptability to particular environments. The pan-genome provides acomprehensive genetic overview of a species and enables comparisons between individual genomes. lt identifies genomic variations like SNPs, InDels, SVs, and PAVs, offering valuable insights into the mechanisms underlying species traits.

Applications


Functional gene localization analysis

Retrieve the missing heritability in complextraits and conduct research on genomicselection breeding

Population epigenetics studies related todomestication and breeding

Provide candidate genes and high-quality genome sequences for gene editingresearch

Highlights


Unlock all genetic information of a particular species

Explore the evolution and diversity of the target species

Fully explore the genetic variation resources of the target species

Workflow


Sample Preparation

Sample Preparation

Refer to: Sample Submission Guidelines

Extraction

Extraction

Refer to Ultra-long DNA
Extraction Protocol / DNA
Extraction Protocol

Sample QC

Extraction
Library Preparation

Library Preparation

Refer to Ultra-long DNA Library Construction Workflow
PacBio Revio DNA Library Construction Workflow

Library QC

Library Preparation
Sequencing

Sequencing

Platform: -Short-read Sequencing: Illumina/DNBSEQ;
-Long-read Sequencing: Nanopore PromethION / PacBio Revio

Data QC

Sequencing
Bioinformatics Ananlysis

Bioinformatics Ananlysis

Pan-genome Demo Report

Click >>

Analysis Workflow


GenomePan genome.png

Publications


Year Journal Impact Factor Title
2026 nature genetics 31.8

Graph pan-genome illuminates evolutionary trajectories and agronomic trait architecture in allotetraploid cotton

2025

Science

 

44.7

Multispecies pangenomes reveal a pervasive influence of population size on structural variation

2025 Nature Communications 16.6

Medicago super-pangenome reveals adaptive advantages and evolutionary constraints in autotetraploid alfalfa

2025 Nature 69.50

A pangenome and pantranscriptome of hexaploid oat

2025 nature genetics 31.8

A pangenome of maize provides genetic insights into drought resistance

 

Contact Us

If you are interested in our long-read sequencing services or potential collaboration, please contact us. Our team is ready to support your research with tailored solutions. We also welcome feedback from users to help us improve our services.

Contact Us
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Contact Us

E-mail:service@sailgene.com

WhatsApp:1-(617)-223-7544

Tel:16172237544

Email:service@sailgene.com

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